How do I make this prayer more effective?

Prayer is most effective when done with a sincere heart and consistency. Establish a quiet time, focus on God's presence, and speak honestly. Combining the "Holy Mary, Help the Helpless" with fasting or reading Scripture can also deepen your spiritual experience.

Can I pray this prayer for someone else?

Absolutely. Intercessory prayer (praying for others) is a powerful act of love. Simply mention the person's name and intention as you pray, asking God to pour His grace upon them.